Contents: Vol. I: I. General Consideration and Biological Aspects: 1. Structure and Function of the Cell. 2. Tools and Techniques in Cell Biology. 3. HeLa Cells. 4. Viruses and Human Cancer. II. Molecule and Membrane: 5. Molecules and Biomolecules of Cells. 6. Enzyme as Biocatalyst. 7. Cell Membrane. III. Bioenergetics and Metabolism: 8. Bioenergetics. 9. Cell Metabolism. 10. Electron Transport and Oxidative Phosphorylation. 11. Photosynthesis. 12. Chemiosmotic Theory. 13. Antimetabolites and Chemotherapy. IV. Fundamentals of Molecular Biology: 14. Heredity, Genes and DNA. 15. Expression of Genetic Information. 16. Recombinant DNA. 17. Detection of Nucleic Acid and Proteins. 18. Gene Function in Eukaryotes. 19. DNA Provirus Hypothesis. 20. RNA Interference. V. Genomes, Proteomics and System Biology: 21. Genomes and Transcriptomes. 22. Proteomics. 23. System Biology. 24. Human Genomes. 25. Synthetic Biology. References. Index.
Vol. II: I. Genes and Genomes: 1. Structure of Eukaryotic Genes. 2. Non-Coding Sequences. 3. Chromosomes and Chromatin. 4. Discovery of Introns. 5. ENCODE Project. II. Replication, Maintenance and Rearrangement of Genomic DNA: 6. DNA Replication. 7. DNA Repair. 8. DNA Rearrangements. 9. Colon Cancer and DNA Repair. 10. Rearrangement of Immunoglobulin Genes. III. RNA Synthesis and Processing: 11. RNA Synthesis and Processing: An Overview. 12. Transcription in Bacteria. 13. Chromatin and Epigenetics. 14. Role of Small Nuclear RNAs in Eukaryotic Gene Expression. IV. Protein Synthesis, Processing and Regulation: 15. Protein Synthesis and Degradation. 16. Translation of mRNA. V. Impotance of Cell Structure and Function: 17. Nucleus and Nuclear Bodies. 18. Nuclear Lamina Diseases. VI. Protein Sorting and Transport : Golgi Apparatus and Lysosomes: 19. Protein Sorting and Transport. 20. Endoplasmic Reticulum. 21. Golgi Apparatus. 22. Lysosomes. VII. Mitochondria, Chloroplasts and Peroxisomes: 23. Mitochondria. 24. Chloroplasts and Other Plastids. VIII. Cytoskeleton and Cell Movement: 25. Cytoskeleton. 26. Motor Protein Kinesin. IX. Cell Walls, The Extracellular Matrix and Cell Interactions: 27. Cell Walls. 28. Extracellular Matrix. X. Cell Signalling and Cancer: Signal Transduction and Oncogenes: 29. Cell Signalling. 30. Cancer: Signal Transduction and Oncogenes. XI. Cell Death and Cell Renewal: 31. Cell Death. 32. Stem Cells. XII. Cancer : Its Causes and Cure: 33. Cancer. 34. Molecular Approaches to Cancer Treatment. References. Index.
Cells are the basic unit of life. In the modern world, they are the smallest known world that performs all of life's functions. All living organisms are either single cells, or are multicellular organisms composed of many cells working together. Cells are the smallest known unit that can accomplish all of these functions. Defining characteristics that allow a cell to perform these functions include: A cell membrane that keeps the chemical reactions of life together, at least one chromosome, composed of genetic material that contain the cell's blueprints and software cytoplasm—the fluid inside the cell, in which the chemical processes of life occur. Thus, cells are the basic building blocks of living things. The human body is composed of trillions of cells, all with their own specialised function. Cells are the basic structures of all living organisms. Cells provide structure for the body, take in nutrients from food and carry out important functions. Cells group together to form tissues, which in turn group together to form organs, such as the heart and brain. Our cells contain a number of functional structures called organelles. These organelles carry out tasks such as making proteins, processing chemicals and generating energy for the cell. The nucleus is based at the centre of the cell and is the 'control room' for the cell. The genome is found within the nucleus. (jacket)